risk stratification – Communicable Diseases Research

Perceived feasibility, facilitators and barriers to incorporating point-of-care testing for SARS-CoV-2 into emergency medical services by ambulance service staff: a survey-based approach

Article

Published on 2022-11-032022-11-15
Journal: BMJ Open
[Category] SARS, 진단,

Serum hydroxybutyrate dehydrogenase and COVID-19 severity and mortality: a systematic review and meta-analysis with meta-regression

Article

Published on 2022-11-012022-11-15
Journal: Clinical and experimental medicine
[Category] 바이오마커,

[키워드] 95% CI Admission alteration Analysis Biomarker certainty of evidence Concentration conducted coronavirus disease COVID-19 COVID-19 patients COVID-19 severity disease severity effect size Egger estimates heterogeneity hospitalized COVID-19 patient hydroxybutyrate hydroxybutyrate dehydrogenase Inflammation Injury Liver damage magnitude marker Meta-analysis meta-regression moderate Mortality mortality. Myocardial myocardial injury non-specific non-survivor Patient performed renal renal function reported risk stratification searched Sepsis serum severity significantly significantly higher SMD standardized mean difference survival survivor systematic review tissue damage Web of Science
[DOI] 10.1007/s10238-021-00777-x PMC 바로가기

Autoantibodies against apolipoprotein A-1 after COVID-19 predict symptoms persistence

Article

Published on 2022-10-012022-11-15
Journal: European Journal of Clinical Investigation
[Category] COVID19(2023년), SARS, 진단, 치료제,

[키워드] AAA1 Accuracy adjusted age and gender analysis anti-apolipoprotein A-1 autoantibodies anti-SARS-CoV-2 association Auto-antibodies contribute correlation COVID-19 COVID-19 symptom declined determine disease severity hospital human monocyte-derived macrophage IFN-α IFN-γ IgG in vitro induce Inflammatory response logistic regression model Long COVID-19 neurological Odds ratio over Participants persistence persistent predict predicted prognostic remained respiratory symptom respiratory symptoms risk stratification ROC Curve SARS-COV-2 infection serology Symptom Symptoms symptoms persistence Trigger type I interferon type I interferon response. were assessed were used with COVID-19 without affecting
[DOI] 10.1111/eci.13818 PMC 바로가기

Predicting a Positive Antibody Response After 2 SARS-CoV-2 mRNA Vaccines in Transplant Recipients: A Machine Learning Approach With External Validation

Article

Published on 2022-10-012022-11-15
Journal: Transplantation
[Category] COVID19(2023년), SARS, 진단,

Advanced cardiac imaging in the spectrum of COVID-19 related cardiovascular involvement

Review article

Published on 2022-10-012022-10-05
Journal: Clinical imaging
[Category] COVID19(2023년), SARS, 바이오마커, 진단, 치료기술,

Biomarkers extracted by fully automated body composition analysis from chest CT correlate with SARS-CoV-2 outcome severity

Article

Published on 2022-09-302022-11-15
Journal: Scientific Reports
[Category] SARS, 바이오마커,

[키워드] 95% CI adipose adjusted analysis Analysis analyzed approach association automated Biomarker body composition Chest Chest CT complex Computed tomography contribute Course death Deceased defined disease disease severity Endpoint endpoints feature female Female patients genders Infection investigated laboratory parameter male Mann-Whitney-U test marker Mortality Multiple multivariate logistic regression outcome Patient patients promoted remained risk risk stratification SARS-CoV-2 SARS-CoV-2 patients severe SARS-CoV-2 severity small patient cohort statistical significance tissue tissues two-sided Volume
[DOI] 10.1038/s41598-022-20419-w PMC 바로가기

Obesity is associated with a higher Torque Teno viral load compared to leanness

Article

Published on 2022-09-282022-11-15
Journal: Frontiers in Endocrinology
[Category] 진단,

Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19

Article

Published on 2022-09-142022-11-15
Journal: Critical Care
[Category] SARS, 치료기술,

[키워드] 95% CI adjusted Antigen association AUROC baseline Clinical deterioration Clinical outcome clinical outcomes clinical status Coagulation collected Concentration correlated correlation correlations Course COVID-19 Cutoff death detectable Enrollment Hospital admission hospitalized COVID-19 hospitalized patient host response ICU admission IL-10 IMPROVE In-hospital increase in Inflammation IP-10 marker mechanical ventilation Multiple multiple logistic regression N-antigen Negative predictive value Pathogenesis Patient plasma plasma biomarker plasma concentration plasma sample Positive predictive value Primary outcome Prognosis prognostic progression prospective observational cohort RAGE risk stratification SARS-CoV-2 SARS-CoV-2 N-antigen SARS-CoV-2 nucleocapsid secondary outcome severe disease significantly Study participants subject tested tissue damage unlikely upper respiratory tract Viral antigen Viral RNA was used were assessed were measured WHO WHO ordinal scale with COVID-19 World Health Organization
[DOI] 10.1186/s13054-022-04153-3 PMC 바로가기

Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group

Article

Published on 2022-09-102022-11-16
Journal: Respiratory Research
[Category] SARS, 치료기술,

[키워드] Acquired Acute respiratory infection Affect Antibiotic treatment Antiviral approach asked Biomarkers CAP pathogens changed community-acquired pneumonia Comorbidities Comorbidity complex complications computer scientist database DelPhi diagnostics disease epidemiologists Europe Guidance Health Host identify imaging immune response immune system Immune-compromised host improvement Influenza internal and external knowledge machine machine learning Mortality next generation sequencing Pathogens patients Personalized medicine Physicians pneumococcal vaccines Pneumonia public health Research resolved risk risk stratification SARS-CoV-2 pandemic second Sequencing shown study group systemic and local The “omics” approach the patient therapy Translational research Treatment Universal Universal influenza vaccine. unmet need Vaccine
[DOI] 10.1186/s12931-022-02117-3 PMC 바로가기

Inflammatory Biomarkers Associated with In-Hospital Mortality in Critical COVID-19 Patients

Article

Published on 2022-09-092022-11-15
Journal: International Journal of Molecular Sciences
[Category] 바이오마커,

[키워드] Analysis AST calculated Clinical course contribute COVID-19 COVID-19 pandemic creatinine Critical critical COVID-19 patients CRP cut-off demonstrated diagnosed with COVID-19 global healthcare groups healthcare identify IL-6 in-hospital mortality in-hospital mortality rate Inflammation Inflammation. Inflammatory biomarker inflammatory parameter INR Kaplan-Meier survival curve laboratory parameter marker Mortality non-survivor parameter Patient patients performed Predictive prognostic reducing retrospective risk stratification ROC significantly higher statistical analysis statistically significant statistically significant difference survival survivor thresholds urea WBC
[DOI] 10.3390/ijms231810423 PMC 바로가기